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The Guatemala experiments are already considered one of the darker episodes of medical research in U.S. history, but panel members say the new information indicates that the researchers were unusually unethical, even when placed into the historical context of a different era.
“The researchers put their own medical advancement first and human decency a far second,” said Anita Allen, a member of the Presidential Commission for the Study of Bioethical Issues.
From 1946-48, the U.S. Public Health Service and the Pan American Sanitary Bureau worked with several Guatemalan government agencies to do medical research – paid for by the U.S. government – that involved deliberately exposing people to sexually transmitted diseases.
The researchers apparently were trying to see if penicillin, then relatively new, could prevent infections in the 1,300 people exposed to syphilis, gonorrhea or chancroid. Those infected included soldiers, prostitutes, prisoners and mental patients with syphilis.

See the full article from “WGCL Atlanta”